Group 5 astronauts and Apollo

Could the Apollo program (not counting Skylab and ASTP) have been
completed without the group 5 astronauts?

It was mainly the group 2 and group 3 astronauts that got us to the
Moon. Nine of the 19 group 5 astronauts were fortunate enough to have
their first flight take them to the Moon. And for eight of those
nine, it was their only flight. The group 2 astronauts and group 3
astronauts except for Anders and Bean that went to the Moon had
previous flights and had been in the program longer.