Jeff Findley wrote:

ISS currently had many redundant systems and modules. With the US and
Russian segments, you have completely separate systems for life support.
Even if something catastrophic happened, it's not very likely to take out
both sets of life support systems.


Unless they close airtight hatches as they move from one module to the
next, one meter hit that blew a foot-wide hole in the thing is going to
vacuumate it in short order.
Even if you were in a sealed-off module, it had better have spacesuits
in it if you want to get to the escape Soyuz.
Even a rescue Shuttle EVA would be a real problem...you'd have to
repressurize the station before you opened the door to the module they
were trapped in, or detach the module with them in it and return it to
Earth.

Pat