Ernie Wright wrote:

The formula Abdul used is pretty standard, and simpler to apply. You
can divide by the parallax (in arcseconds) or multiply by the distance
(in parsecs).

4.74 is just a constant of proportionality that converts between AU/year
and km/s. An object at a distance of 1 parsec with a proper motion of 1
arcsecond/year has a transverse motion of 1 AU/year, or 150 million
km/year, or 4.74 km/s.

Oh, so that's where the 4.74 came from, I wasn't sure of its origins.

So to depart toward Alpha Centauri on a hypothetical voyage, one has
to leave the ecliptic plane of our solar system going south towards
-60° 50' declination.
Is there an easy calculation to work out how many degrees that
direction is off the ecliptic plane of our solar system?

Abdul